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A second enzyme, NADPH-cytochrome P 450 oxidoreductase, transfers electrons to the CYP where it can, in the presence of O 2 , oxidize xenobiotic substrates, many of which are hydrophobic and dissolved in the ER

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Bayo Jimenez M.T., Gericke A., Frenis K., Rajlic S., Kvandova M., Krller-Schn S., et al

Contrasting neuroendocrine responses in depression and chronic fatigue syndrome

As indicated below, different combinations of the M and H subunits generate LDH isoforms in different tissues