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153,154 In this context, NOX-derived ROS are logical contributors to these phenomena, although the exact function of these enzymes in cellular alteration remains unclear

High Se status was associated with decreased risk of hyperglycemia and type 2 diabetes, while other studies also reported that high serum Se concentration favored increased prevalence of diabetes male participants followed over 9 years

Therefore, therapeutic approaches that either directly inhibit the xCT pathway or target metabolic vulnerabilities may be effective in overcoming ferroptosis resistance

8A), an indicative of high binding affinity between the two proteins

Exp Mol