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(2018) PCO-02 - Safety and pharmacokinetics trial - Full Text View - ClinicalTrials.gov

In adults, the liver was identified as the target of APAP toxicity in the 1960s [6-8]
However, many other phytochemicals more directly target inflammation: celastrol, for example, powerfully inhibits NFB, a master regulator of inflammation, thereby reducing downstream cytokines and slowing neurodegenerative inflammation [51]
