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& Hellstrom, W.J.G
n=141 ALC, n=139 control), the pooled estimate also favored ALC, though the confidence interval included the possibility of no effect (SMD 1.33, 95% CI 2.80 to 0.14
As genetic variants are determined at conception they are much less affected by the confounders that can bias conventional observational studies, such as socioeconomic position, so MR studies minimize confounding
Proc Natl Acad Sci U S A 117(33):19982-93 2020 PMC7443878 Shao B, Mathew AV, Thornock C, Pennathur S, Michigan Kidney Translational Core CPROBE Investigator Group
