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Interferon- (IFN-) predominantly acts through the JAK1/2-STAT1 pathway to induce M1 polarization, enhancing the expression of other proinflammatory factors such as IL-6 and tumor necrosis factor- (TNF-), with TNF- being a potent promoter of M1 polarization as well as a significant inhibitor of M2 polarization [47]

Vitamin C supports the normal functioning of the immune system and the formation of collagen, promoting skin health, while selenium contributes to the maintenance of hair and nails

DybiecJFrakWKumierzJTokarekJWojtasiskaAMynarskaEet al

To check whether the attenuation of hepatotoxicity was dependent on GSDME inhibition, we compared transaminase activities and inflammatory cytokines levels in WT and Gsdme / mice in the presence or absence of MeCbl