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While specific therapies for IBM are still lacking, NAD + boosters have shown promising results in various models, including nematodes with amyloid aggregation, aged rodents, and human muscle cells from IBM patients

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This study also reported elevated citrate synthase activity, which was speculated to reflect enhanced mitochondrial biogenesis

Cyanocobalamin, by contrast, requires enzymatic conversion in the liver and tissues to become active

This makes it simple and convenient for research
