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These findings lend support to ours, where the depicted MSG-induced upsurge in glutamate levels, oxidative stress and neuroinflammation, provided possible explanation for the excessive ER stress noted in this group, evinced by marked upregulation in the gene expression ER stress markers, PERK/CHOP/GRP78, compared to normal control group

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[DOI] [PubMed] [Google Scholar] [86].Barbaro G, DiLorenzo G, Soldini M, Parrotto S, Bellomo G, Belloni G, et al

elegans lifespan, but it significantly and dose-dependently shortened the median animal lifespan (Fig
