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Endothelial dysfunction can disrupt homeostasis, increasing the risk of atherosclerotic disease and hypertension

We determined the duration of the washout period based on the estimated complete turnover time of GSH synthesis in the brain ( Randomization The study randomization and intervention timeline are illustrated in Figure 2

Although disorders of absorption and transport are associated with hyperhomocysteinemia, this is not as marked as that arising from intracellular defects

This investigation found no correlation between plasma cysteine and nutritional status, pointing to impairment of trans-sulfuration as the major cause

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