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8-OHdG serves as a biomarker of oxidative stress in spermatozoa and has been linked to chromosomal instability and mutagenesis (67, 68)

Poorly managed therapeutic insulin can cause diabetic patients to experience broad fluctuations in glucose concentrations, ranging from hyperglycemic to hypoglycemic states

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For example, the accumulation of lactate and lipid droplets in the microenvironment may modulate immune cell function, thereby influencing GBM progression (32)

Integrative miRNA and gene expression profiling analysis of human quiescent hepatic stellate cells