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In primary care, orlistat is commonly prescribed, working by inhibiting pancreatic lipase to reduce dietary fat absorption

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NAD+ enhancement has been shown to reduce neuroinflammation and improve cognition in models of neurodegeneration [3]

Such findings led scientists to label AOD-9604 as the worlds first drug with a metabolic mechanism of action for obesity meaning it works by accelerating fat metabolism rather than suppressing appetite

Additionally, there was variability between the included studies in the follow-up duration, which may cause heterogeneity in the results obtained