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Prior studies of patients with relapsed myeloid malignancy treated on a clinical trial with ipilimumab demonstrated similar CD8 T cell infiltration and exhaustion reversal in disease biopsies (185, 186)
Aytar elik P, Erdogan-Gover K, Barut D, Enuh BM, Amasya G, Sengel-Trk CT, et al

NOS uncoupling results in reduced synthesis of NO and enhances the capability of the enzyme to produce ROS [67]
J.van der TweelI.AlgraA.KlijnC

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