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Well, we don't really

Methylcobalamin aids in maintaining healthy nerve function and the regeneration of damaged nerves

2010;16(3):BR81-88

For that reason, an untreated pernicious anemia often leads to neurological damage, which should explain why so many patients with neurological disorders such as Alzheimer, multiple sclerosis, peripheral neuropathy, and Bells Palsy, benefit from B12 shots

Controversy persists regarding their effectiveness in reducing pain and improving the function
