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There does seem to be some genetic susceptibility, as it does seem to run in families, and men with PD are also more likely to develop Dupuytrens contracture a condition where plaques develop on the tendons of the hand causing the fingers to curl (as can be seen with the actor Bill Nighy)

Zare Z, Masteri Farahani R, Salehi M, Piryaei A, Ghaffari Novin M, Fadaei Fathabadi F, et al