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Dadurch knnen neben der Pigmentierung auch andere physiologische Effekte beobachtet werden, was zu einem unterschiedlichen Nebenwirkungsprofil fhrt

Wang L, Wang H, Morizono H, Bell P, Jones D, Lin J, McMenamin D, Yu H, Batshaw ML, Wilson JM (2012) Sustained correction of OTC deficiency in spf (ash) mice using optimized self-complementary AAV2/8 vectors

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However, it is possible to remove them surgically or with laser therapy for aesthetic purposes
