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Folliculitis: Recognition and Management

Endocrine Versus Paracrine Autocrine IGF-I One of the controversies of the area has been the relative contribution to linear growth of circulating endocrine IGF-I largely produced by the liver versus peripherally produced IGF-I with major paracrine/autocrine actions on local tissues

Start conservatively and adjust based on results

This goes beyond simple wound closure to actual functional restoration

However, the 2.65 improvement over the 3-session protocol (which used the same ingredients) and the results exceeding typical minoxidil-only or microneedling-only studies suggest the copper peptide component adds meaningful value