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Toxicant Burden and Sensitivities: By heavily upregulating Phase II liver detoxification enzymes (GSTs) and providing direct heavy metal chelation, NAC helps the body safely process and excrete environmental toxins, potentially reducing systemic chemical sensitivities
Initial work predicted several SKN-1 binding sites to be present in the gss-1 gene promoter region [66]
Proper aftercare and hygiene are crucial to prevent this
Therefore, modulating autophagy may offer a novel intervention strategy for improving DOR
