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Description
OncoImmunology (2016) 5(8):e1184802
Under physiological conditions, lung tissues exhibit a unique metabolic preference: approximately 40% of glucose is converted to lactate via glycolysis despite adequate oxygen availabilitya phenomenon reminiscent of the Warburg effect observed in cancer (Lee et al., 2004
Although transient UPR activation is protective, chronic zinc deficiency amplifies ER stress signaling, promoting apoptosis and inflammation
In contrast to p53, the p53-related protein p73, which promotes cell proliferation, induces the expression of G6PDH and facilitates the PPP 46
doi: 10.1042/bss0660167
