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Amide analogues of trichostatin A as inhibitors of histone deacetylase and inducers of terminal cell differentiation

The results illustrated that the loaded drug exhibited higher cytotoxic potential (based on MTT assay) on human leukemia cells (HL60) and lung fibroblast cells (V79) in comparison with the free drug

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Low levels of glutathione can increase oxidative stress and contribute to insulin resistance