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Science 318 (5858), 19171920

BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states (Nature Metabolism, 2025) Summary: This study identifies how melanoma cells control iron inside the cell by focusing on the enzyme BDH2 at mitochondrialysosome contact sites

Exposure to pristane for 12 or 24 weeks promoted macrophage activation syndrome, characterized by hemophagocytosis in spleen and peripheral blood, as well as hypercytokinemia of IFN-, TNF-, IL-4, and IL-6

L-carnitine versus B12 Tirzepatide with B12 is probably the most common compounded combination