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After multiple once-daily dosing of divalproex sodium extended-release tablets, the peak-to-trough fluctuation in plasma valproate concentrations was 10 to 20% lower than that of regular divalproex sodium delayed-release tablets given BID, TID, or QID

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Sleep is involved in regulating heat, maintaining energy, and recovering tissues

Contextually, this kind of intervention could be easily implemented during the early postoperative period
