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Description
To provide quantitative data on the possible role of HNE in oxidative genotoxicity, we applied an accurate HPLC-MS approach to the quantification of HNE adducts to DNA and of HNE conjugates to glutathione (HNE-GSH), the product of the major detoxification pathway of HNE in cells
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For in silico analysis, we screened two public datasets, GSEA M5190 and TCGA SARC
