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When stimulated with exogenous TGF, NHBE and NHLF monocultures showed a significant upregulation of EMT (COL1A1, FN1, VIM, ASMA) and senescence (P21) markers, respectively
In women, it aids in triggering the final maturation of the ovarian follicle, precipitating ovulation and thereby maximizing the chances of conception
Altogether our results demonstrate that GSTP1/2 are a critical regulators of hepatocyte proliferation in the initial phases of liver regeneration.
