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Description
Diminishing returns
Some patients choose optional lab work for optimization ($100-$200), but this isn't required

Modic changes Vertebral bone marrow signal intensity changes observed on MRI, commonly in association with intervertebral disc degeneration

Likewise, with NO-agents it could be not established that the effect on mucosal presentation was extended to a comparable sphincter function

doi: 10.1038/npp.2014.9 152 JackaFN