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CrossRef HMGB1 Regulates Adipocyte Lipolysis via Caveolin-1 Signaling: Implications for Metabolic and Cardiovascular Diseases Julia Chu-Ning Hsu, Kuan-Ting Chiu, Chia-Hui Chen, Chih-Hsien Wang, Song-Kun Shyue, Tzong-Shyuan Lee International Journal of Molecular Sciences.2025

Reproductive toxicity of cadmium in pubertal male rats induced by cell apoptosis

This systematic review of the 13 controlled trials in 3,629 patients, involving 250 deaths, 220 cases of new heart failure, and 38 recurrent heart attacks, found that L-carnitine was associated with: Significant 27% reduction in all-cause mortality (number needed to treat 38) Highly significant 65% reduction in ventricular arrhythmias (number needed to treat 4) Significant 40% reduction in the development of angina (number needed to treat 3) Reduction in infarct size There were numerically fewer myocardial reinfarctions and heart failure cases associated with L-carnitine, but this did not reach statistical significance.First author James J

International Journal of Molecular Sciences, 25 (16), Article 9118

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Pontarollo G., Kollar B., Mann A., Khuu M.P., Kiouptsi K., Bayer F., et al