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Description
After exocytosis, membrane PAM appears on the plasma membrane, where it is rapidly internalized and is either packaged into secretory granules or undergoes degradation (Milgram et al., 1994

10.1006/abbi.1996.0482 37 KarunakaranS.SaeedU.RamakrishnanS.KoumarR
doi:10.1067/mlc.2002.129504 Chen JJ, Thiyagarajah M, Song J, Chen C, Herrmann N, Gallagher D, et al

doi: 10.1038/s41598-021-01529-3

Tregs themselves are vital in peripheral immune tolerance and suppressing autoimmunity and inflammation through control of adaptive and innate immune responses (Shi et al., 2022)
