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Moreover, iron deposition and its associated molecular mechanisms, including alterations in the expression of DJ-1 and SLC7A11 genes, as well as the production of lipid peroxides, are closely related to ferroptosis in Parkinsons disease (Lind-Holm Mogensen et al., 2023

OLGs located at the border of the lesion produce heparan sulfates, which, in turn, enhance remyelination via Sonic Hedgehog signaling (Macchi et al., 2020)