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Apoptosis is the most commonly studied type of cell death in the cuprizone model as it is well understood and easy to assess

6.4 Activation of inflammatory pathways The inflammatory mechanisms that result from acute and chronic brain injury is mediated by both innate and adaptive immune system responses

Methods 38 ClarkR.BayirH.ChuC.AlberS.KochanekP.WatkinsS

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Methods Chemicals Scopolamine hydrobromide and Donepezil hydrochloride were brought from Merck (Merck KGaA, Darmstadt, Germany).Trichloroacetic acid, acetylthiocholine iodide, 5,5-dithiobisnitrobenzoic acid (DTNB), hydroxylamine hydrochloride, and ferric chloride, were brought from Sigma-Aldrich (St
