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Current proximity labeling enzymes fall largely into two classes: the peroxidases and the biotin ligases (Fig

In contrast, cysteine (Cys) and threonine (Thr) deprivation led to cell death via distinct pathways: ferroptosis for Cys starvation, whereas Thr deprivation triggered a previously uncharacterized form of cell death, which could be entirely suppressed by methionine (Met) co-starvation, and mTOR or translational inhibition

Hereditary pancreatitis : Rare genetic causes (such as PRSS1 mutations) may increase susceptibility to pancreatitis

doi: 10.1016/j.jmb.2009.08.038