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BMJ Open 12 (3), e053772
doi: 10.1101/gad.334219.119 89 VermaA.HirschD
doi: 10.1681/ASN.2004060436
Compared with structural changes, metabolic biomarkers may be more sensitive and helpful to further our understanding of the underlying pathophysiological mechanisms of ME/CFS
(58) performed single-nucleus RNA sequencing (snRNA-seq) on DCM, HCM, and non-failing heart samples, which led to the identification of transcriptional alterations and cellular sub-population changes in disease states, particularly fibroblast activation characteristics, which expanded the current understanding of pathomechanisms
