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A lot of them succeeded, some did not, Esser said

J Inherit Metab Dis 19:6575

In the European Food Safety Authority (EFSA) Panel on Food Additives and Nutrient Sources added to Food (ANS) adopted a scientific opinion on the re-evaluation of the food additive color curcumin (E 100) (turmeric rhizome extract) and concluded that the available data set supports the ADI allocated by JECFA based on the NOAEL of 250320 mg/kg bw per day from the reproductive toxicity study in rats for a decreased body weight gain in the F2 generation observed at the highest dose level, and an uncertainty factor of 100 (259, 260)

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Bacteriostatic Water Use 3.0 mL per vial for reconstitution