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Additionally, unexpected hypoglycemia, severe gastrointestinal symptoms beyond typical tirzepatide effects, or allergic reactions may indicate formulation problems

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A 2024 study showed that people with homozygous (TT) or heterozygous (CT) MTHFR variants had statistically significant lower hemoglobin than controls
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[DOI] [PubMed] [Google Scholar] 117.Rokkas T., Niv Y
