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Modest metabolic benefits: Some studies have shown small benefits like a slight decrease in LDL cholesterol, but these effects dont persist after discontinuation
use caution in Lebers hereditary optic neuropathy and discuss risks if youve had B6-related neuropathy or severe kidney disease
The disorder has severe to moderate clinical variants [23]
Patients do best and experience fewer side effects if they gradually increase their doses of all diabetes and weight-loss drugs, Low Wang said
