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Overexpression of human AADAC in Huh-7 cells significantly attenuated carbon tetrachloride-induced cytotoxicity by suppressing ferrous iron accumulation, suggesting that AADAC interacts with CP to suppress hepatic ferrous iron accumulation

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GPX4 expression was associated with poor OS and DFS, especially in lung adenocarcinoma (p=0.008, and 0.027, respectively)

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