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A deficiency in n-3 PUFAs can lead to neuroinflammation, cognitive impairments, suboptimal neurogenesis, neurotransmitter metabolism defects, and impaired brain growth and development, thereby affecting the progression of NDDs such as AD

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Enlargement can occur, presumably due to macrophage migration, resorption of underlying bone, or continued corrosion [49]

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USP22 directly interacts with and deubiquitinates PPAR, which is stabilized by K48-linked deubiquitination

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Always confirm the exact vial strength, dilution amount, and instructions on your prescription label

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Future research must shift from descriptive association to mechanistic intervention, aiming to target the gut microbiota-metabolite network and thereby establish a new therapeutic paradigm that improves upon the traditional tumor-centric view

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