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Rice Sharon Woodard Abbie Wrights

DOI:10.1194/jlr.R067629 [Google Scholar] Tvrzicka E, Kremmyda LS, Stankova B, Zak A

On rare occasions, it can produce features similar to primary biliary cirrhosis due to progressive destruction of small bile ducts (vanishing duct syndrome)

The mechanism is not entirely clear but it is hypothesized that the reduction in homocysteine from B vitamin supplementation may exert favorable and protective effects on nerve demyelination (31), and may attenuate the neurotoxic effects of homocysteine and N-methyl-D-aspartate (NMDA) agonists (32)

These effects were observed across multiple organ systems and disease models, highlighting its broad therapeutic potential
