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Characterized by its insidious onset, poor prognosis and limited treatment options, initial prevention of lesions in DR carries profound clinical and societal significance, before visual symptoms become irreversible

Evidence for a role of advanced glycation end products in atrial fibrillation

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PMID: 65 GautamPKKumarSTomarMSSinghRKAcharyaAKumarSet al

282 Mechanistically, this might occur via the downregulation of TJ-related mRNA expression (e.g., occludin, CLDN1/3/4, and ZO-1)
