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Urine yesterday was dark, which is not normal for me at all since I stay well hydrated, and Im thinking this is either a kidney infection or stone, which I had once before., about 15 years ago

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A water molecule coordinated to a metal ion is more acidic than a free water molecule for two reasons

Beyond the absolute contraindications, several situations call for heightened caution in the class framing and are firmly a clinicians domain: a history of pancreatitis or symptomatic gallstones, significant gastrointestinal motility disorders (such as gastroparesis, which slowed gastric emptying can worsen), diabetic retinopathy that is not stabilized, severe renal impairment where dehydration from GI side effects raises risk, and any concurrent use of insulin or a sulfonylurea, where the additive glucose-lowering can produce hypoglycemia