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Description
This is the expert-level detail that separates inconclusive data from a genuine breakthrough

T.et al (2014)

Gut 63 (5), 727735

Important caveats Large-scale, long-term human outcome data are limited

For instance, it has been demonstrated that NR supplementation is safe up to 3000 mg daily, with readouts reported for NAD + levels, mitochondrial function, and clinical phenotypes measured in several trials 246,310313