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doi: 10.3389/fendo.2024.1440182 Received 29 May 2024 Accepted 26 August 2024 Published 18 September 2024 Volume 15 - 2024 Edited by Kuan-Hao Tsui, Kaohsiung Veterans General Hospital, Taiwan Reviewed by Xiuliang Dai, Changzhou Maternal and Child Health Care Hospital, China Rui Yang, Peking University Third Hospital, China Updates Copyright 2024 Zhao, Liu, Zhang, Sun, Zeringue, Meng and Ma

Finally, pre- and post-synaptic GABAergic inhibition is lost and this may produce paradoxical excitation, contributing to neuron hyperexcitability and even to spontaneous neuron activity 146