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In summary, the involvement of GSH in the carcinogenesis and in the drug resistance of tumor cell is clear, but further studies, aimed at understanding the GSH-driven molecular pathways, might be crucial to design new therapeutic strategies to fight cancer progression and overcome chemoresistance

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observed that the KD may decrease neuronal excitability in the lateral habenula (LHb), a brain region responsible for the development of MDD

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In the nucleus of hepatocyte, the active form of PKA leads to the activation of transcription factor CREB that links the active site of CRE on PGC-1 gene promoter