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Circumstantial evidence for this hypothesis comes from one cohort study in which the combination of low B12 and high folate status was associated with lower serum holotranscobalamin concentrations than when B12 was low but folate was not elevated (81)

Micronutrient deficiency is a leading cause of many health issues, including fatigue

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doi:10.1155/2012/324832 Philp D, Goldstein AL, Kleinman HK

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