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The steroid treatment was oral prednisone, 1 mg/kg daily (max dose 60 mg daily), for 1214 consecutive days

An increased number of karyopyknotic cells was found in all four regions: cerebral and cerebellar cortex, hippocampus cortex, and hypothalamus/thalamus in control rats (Figure 8 and Figure 9)

Pathengay, A., Flynn, H

In severe acute pancreatitis (SAP), inflammatory factors promote the expression of matrix metalloproteinases (MMPs) and heparinases, which degrade syndecan-1 (SDC-1) and HS, while oxidative stress disrupts HA-CD44 binding, leading to increased capillary leakage and neutrophil adhesion