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Description
Adolescents whose brains are still developing are more vulnerable than adults to ketamine-induced neuronal apoptosis and cognitive deficits ( Comorbid conditions, such as diabetes and chronic kidney disease, amplify ketamines neurotoxicity by increasing oxidative stress and impairing drug metabolism
It has been shown that ROS generation mainly occurs by the activation of a plasma-membrane NADPH oxidase (Drerup et al
doi: 10.1136/gut.40.6.767
doi: 10.1016/j.jtemb.2020.126500 8 HouKLiuLFangZ-HZongW-XSunDGuoZet al
JZ: Resources, Writing review and editing
