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ROS release was decreased by astaxanthin after treatment with hemoglobin in a human brain endothelial cells modeling hemorrhage in vitro [191]

Furthermore, although AX often forms fatty acid esters in nature, it has been reported that there is no essential difference in the first oxidation potential between AX and its n-octanoic mono- and diesters

PMID: 126 ShaoJBaiZZhangLZhangF

Interestingly, in this study, cGMP coordinately increased the expression of both GPx-1 and catalase in a manner dependent on protein kinase G-dependent mechanisms