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Do not self-administer without professional direction

Since cross-reactivity, including bronchospasm, between aspirin and other nonsteroidal anti-inflammatory drugs has been reported in such aspirin-sensitive patients, diclofenac sodium extended-release tablets should not be administered to patients with this form of aspirin sensitivity and should be used with caution in all patients with preexisting asthma

Its analytical verification, purity standards, and quality-control testing support its use in controlled experimental environments

However, the BfR recommends limiting the daily intake to a maximum of 9 g, i.e

Note that impairment of alertness, judgment, and coordination can occur at BACs well below the legal limit for driving a vehicle