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because selenium is part of the enzyme glutathione-peroxidase Glutathione peroxidase-1 and neuromodulation: Novel potentials an old The effectiveness of compound “X”
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doi: 10.1016/S1474-4422(11)70261-7 85 Gil-BeaF
Even though these drugs somewhat effectively manage the diseases symptoms, they do not represent restorative treatments

In addition, berberine is small in size, so it can available through the blood-brain barrier and effectually act on molecular target, showing great therapeutic potential in the treatment of neurodegenerative diseases (Wang et al., 2005

doi: 10.1038/s41598-019-53965-x 143 TerkeltaubRLeeJMinJShinSSaagKG
