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(2000) revealed that pretreatment with 7-NI before METH injection afforded protection against the depletion of dopaminergic markers induced by METH, but did not affect persistent hyperthermia at a low dose

In those patients, addressing the underlying metabolic dysfunction first, through dietary intervention, GLP-1 therapy if indicated, or NAD+ support for cellular energy metabolism, is the clinical priority

Three other potential treatments are being studied in clinical trials

N-Acetyl L-Carnitine is a form of L-Carnitine
