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Mar 2018;43:100-108

In vitro models and ex vivo systems used in inflammatory bowel disease

The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages
Ferroptosis has also been reported to be associated with damage to the locus coeruleus noradrenergic neuronal degeneration, and the occurrence of non-motor symptoms such as learning and memory dysfunction, which take place in the early stage of PD (Hou et al., 2019b)