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Keywords: oxidative stress, nutraceuticals, astaxanthin, superoxide dismutase (SOD), neurodegeneration, Alzheimer's disease Abstract Oxidative stress, the imbalance of the antioxidant system, results in an accumulation of neurotoxic proteins in Alzheimer's disease (AD)

These include the Sperm Chromatin Structural Assay (SCSA), Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), Comet, and Sperm Chromatin Dispersion (SCD) assays [49]

If not eliminated by GPX4, the resultant accumulation of lipid peroxidation products drives ferroptosis

This finding suggests the contribution of this enzyme to the mucosal defense system of the equine intestinal tract [62]