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Nevertheless, key questions remain regarding the enzymatic control, cell-type specificity, and in vivo relevance of lactylation, warranting deeper mechanistic and translational investigation

for the labeled group, the fresh medium contained 100 ng/ml LPS, 25 mM [U- 13 C]-glucose, 4 mM [U- 13 C]-glutamine, 5 mM [U- 13 C]-acetate in glucose-free and glutamine-free DMEM

doi: 10.4103/1673-5374.374142, 164 YaoS.XuM